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KMID : 1145520220080020119
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Journal of Radiopharmaceuticals and Molecular Probes
2022 Volume.8 No. 2 p.119 ~ p.128
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Challenge of 2-dimensional Inorganic Nanoparticles in Nuclear Medicine
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Eom Sai-Ran
Choy Jin-Ho
Lee Kyo-Chul
Lee Yong-Jin
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Abstract
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2-Dimensional inorganic nanoparticles with high surface area and ion-exchangeable properties have been continuously growing based on nanotechnology in the field of nanomedicine. Among one of the 2-D nanoparticles, layered double hydroxide (LDH) has been intensively explored as drug delivery due to its low toxicity, enhanced cellular permeability, and high drug loading capacity. Moreover, controllable chemical composition makes possible varying isomorphic layered materials for therapy and imaging of diseases. In this review, specific structural characteristics of LDH were introduced, and its potential for application as a biocompatible therapeutic agent and diagnostic one was addressed in nuclear medicine, one of promising fields in nanomedicine.
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KEYWORD
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2-Dimensional inorganic nanoparticle, Layered double hydroxide, Nuclear medicine
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